Septicemia or toxemia is a condition where microbes such as bacteria or toxins invade the blood stream and other body organs. Snakes with septicemia are critically ill and are often near death. They exhibit lethargy, lack of appetite, open-mouth breathing, and often have a red discoloration on the scales of their bellies. Septicemia is a true emergency that requires aggressive treatment in the hospital. Antibiotics, fluid therapy, and force-feeding are needed in an attempt to save the snake.